TrumpRx Savings Calculator: How Much Will You Save on GLP-1 Drugs?
I was talking to a patient last month who had been on Wegovy for eight months — paying $1,350 every single month out of pocket. When I showed her the TrumpRx MFN price of $349, she went quiet for a moment. Then she did the math out loud: "That's $8,008 I've already overpaid." That's the number that matters. Let me help you calculate yours.
This page gives you a clear, scenario-by-scenario breakdown of how much TrumpRx pricing saves compared to retail, GoodRx, and the manufacturer's list price — so you know exactly what you're working with before you fill your next prescription.
How to Calculate Your TrumpRx Savings
The math is simple. Take what you're currently paying, subtract the TrumpRx MFN price, and multiply by the number of months you expect to be on the medication. Here are the key reference prices to use (as of May 2026):
| Medication | Your Current Cost (estimate) | TrumpRx MFN Price | Monthly Savings |
|---|---|---|---|
| Ozempic (retail) | ~$900/mo | ~$285/mo | ~$615/mo |
| Ozempic (GoodRx) | ~$820/mo | ~$285/mo | ~$535/mo |
| Wegovy (retail) | ~$1,350/mo | ~$349/mo | ~$1,001/mo |
| Wegovy (GoodRx) | ~$1,150/mo | ~$349/mo | ~$801/mo |
Use our free GLP-1 cost calculator to enter your specific drug, dose, and insurance status and get a personalized savings estimate in under 60 seconds. It compares TrumpRx pricing against all major savings options side by side — including manufacturer programs, GoodRx, and telehealth alternatives.
Savings By Treatment Duration
GLP-1 treatment is typically long-term — often 12 to 24 months or ongoing. Here's what the savings look like compounded over time:
Ozempic Savings Over Time (retail vs. TrumpRx, ~$615/month)
| Duration | Retail Total | TrumpRx Total | Total Savings |
|---|---|---|---|
| 3 months | $2,700 | $855 | $1,845 |
| 6 months | $5,400 | $1,710 | $3,690 |
| 12 months | $10,800 | $3,420 | $7,380 |
| 24 months | $21,600 | $6,840 | $14,760 |
Wegovy Savings Over Time (retail vs. TrumpRx, ~$1,001/month)
| Duration | Retail Total | TrumpRx Total | Total Savings |
|---|---|---|---|
| 3 months | $4,050 | $1,047 | $3,003 |
| 6 months | $8,100 | $2,094 | $6,006 |
| 12 months | $16,200 | $4,188 | $12,012 |
| 24 months | $32,400 | $8,376 | $24,024 |
Over two years on Wegovy, the difference between retail pricing and TrumpRx MFN pricing is $24,024. That's not an abstraction. That's a car, a college semester, a down payment. These numbers are why I keep writing about this — because most patients don't know the math until someone shows them.
Who Saves the Most from TrumpRx?
The biggest savings go to the patients who have been paying the most — uninsured patients paying full retail with no assistance. Let me break it down by common patient profile:
Profile 1: Uninsured Patient, Ozempic at Retail
Current monthly cost: ~$900. TrumpRx monthly cost: ~$285. Monthly savings: $615. Annual savings: $7,380. This patient's savings are immediate and dramatic from the first fill.
Profile 2: Employer Insurance That Excludes GLP-1s for Weight Loss
This is one of the most common situations I see — insurance that covers GLP-1s for diabetes but not for weight management. If you're in this group and paying out-of-pocket, TrumpRx eligibility likely applies to you. Same savings profile as an uninsured patient for the GLP-1 prescription.
Profile 3: GoodRx User, Ozempic
Current monthly cost: ~$820. TrumpRx monthly cost: ~$285. Monthly savings: $535. You're already saving vs. retail — but TrumpRx saves you an additional $6,420 per year over what GoodRx gets you.
Profile 4: Commercially Insured, $150 Copay After Deductible
Here's where it gets nuanced. If you have commercial insurance and you're paying $150/month for Ozempic after your deductible, TrumpRx probably saves you $135/month — meaningful, but not the same dramatic shift. And you'll need to check whether your insurance status makes you ineligible for TrumpRx. Manufacturer copay cards may still be your best option in this situation, potentially bringing your cost to $0-$25.
How to Use the Calculator for Your Scenario
Our GLP-1 cost calculator lets you enter your specific situation and get a personalized estimate. Here's what it accounts for:
- Which GLP-1 medication and dose you're on
- Your current insurance status and coverage
- Your current monthly out-of-pocket cost
- Which savings programs you may qualify for, ranked by potential savings
The calculator is free, takes under a minute, and gives you a side-by-side comparison you can bring to your pharmacist or doctor's appointment. Run your numbers before your next fill — the difference between what you're paying and what you could pay is almost certainly worth knowing.
Stacking TrumpRx With Other Programs
Here's what they don't tell you: for some companion medications you take alongside your GLP-1, other discount programs may offer better pricing than TrumpRx. The smart approach is not to pick one savings program and ignore the rest — it's to use TrumpRx for your GLP-1 and GoodRx or similar programs for your other prescriptions.
You cannot use two programs simultaneously for the same prescription fill. But across your full medication list, a layered approach often delivers the maximum total savings. Our calculator accounts for your full drug spend, not just the GLP-1 line item.
Compare GLP-1 telehealth programs alongside TrumpRx
Oak Weight Loss offers personalized GLP-1 programs with compounded semaglutide and dedicated health coaching. For patients who don't qualify for TrumpRx or who want coached support alongside their medication, Oak's pricing often competes with MFN-level costs — with a licensed provider included.
See Oak's GLP-1 Program →Affiliate link — we may earn a commission at no extra cost to you
The Number That Matters Most
I keep coming back to that patient who had overpaid $8,008 over eight months. The number that matters to you is different — it depends on which drug you're on, what you've been paying, and how long you've been at that price. But whatever it is, you deserve to know it.
Run the calculation with our GLP-1 cost calculator. Check TrumpRx.gov to confirm your eligibility. And at your next pharmacy visit, pay the price the system should have offered you from the beginning.