⚡ Novo Nordisk announced ~50% list price reductions on Wegovy and Ozempic — announced for 2027

Best GLP-1 Telehealth Programs 2026

Compounded semaglutide and tirzepatide programs start at $30–$149/mo — a fraction of retail pharmacy prices. We compared 22 providers on price, coaching, availability, and guarantees.

22 programs comparedPrices from $30/moUpdated June 2026

Find Your Best Match

Answer the questions below — we'll highlight the programs that fit.

Do you have health insurance?

Monthly budget for medication?

Injection or pill?

Do you want coaching or provider support included?

Full Comparison: 22 Programs

ProviderStarting Price
Oak Weight LossPersonalized pricing
DudeMedsFrom $30/mo
Yucca HealthFrom $300/mo
Synergy RxFrom $199/mo
Embody GLP-1From $249/mo
Care Bare RxFrom $199/mo
TrimRxFrom $199/mo
Strut HealthFrom $125/mo
Bodybuilding Health+From $96/mo
Eden HealthFrom $149/mo
Novi Weight LossPersonalized — from ~$199/mo
System LabsFrom $59/mo
WellorithmFrom $147/mo
TonikFrom $199/mo
EnhanceMDFrom $212/mo
Ro (Roman)From $299/mo
Hims & Hers$199–$349/mo
Noom Med$149–$199/mo
WeightWatchers ClinicFrom $99/mo + WW
CalibrateFrom $199/mo
Form HealthFrom $99/mo
KnownwellVaries by insurance

* Some programs are affiliate partners. We may earn a commission if you enroll, at no cost to you.

Hidden Costs to Watch For

The advertised price rarely covers everything. Here are six add-ons that can double your actual monthly cost.

🧪

Lab Work

Most programs require a metabolic panel before prescribing. Labs typically run $50–$150 unless your PCP orders them.

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Dose Escalation

Starting doses are low. Monthly cost often increases as you titrate up to maintenance doses — sometimes 2× the starting price.

🥗

Coaching & Nutrition

Basic telehealth scripts rarely include coaching. Programs that add it (SHED, Oak, Noom) charge $50–$150/mo more.

📹

Video Consults

Some platforms charge per follow-up visit ($25–$75 each). Others include unlimited messaging — clarify before signing up.

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Shipping & Supplies

Compounded injections require needles, syringes, and alcohol wipes. Budget $10–$25/mo for supplies not included in base price.

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Prior Auth & Appeals

If using insurance for branded GLP-1s, prior auth is almost always required. The process can take 2–6 weeks and may be denied.

Program Deep Dives

Our affiliate partners — full details on what's included and who each program is best for.

Oak Weight Loss

Personalized Program

Personalized GLP-1 weight loss with dedicated health coaching

Personalized pricing

Drug

Semaglutide

Coaching

Yes — dedicated coach

States

Most states

Best For

Personalized care

A dedicated health coach walks you through every step — unusual at this price point.

Get Started

DudeMeds

Men's Health

GLP-1 + men's health — discreet, doctor-prescribed, delivered

From $30/mo

Drug

Semaglutide

Coaching

No

States

Most states

Best For

Men's health bundle

Starting at $30/mo, lowest price we've found. Built for men — bundles ED and testosterone options.

Get Started

Yucca Health

All 50 States

Semaglutide + tirzepatide programs — all 50 states

From $300/mo

Drug

Semaglutide / Tirzepatide

Coaching

Basic

States

50 states

Best For

All-state availability

Available in all 50 states. Offers both semaglutide and tirzepatide — rare at a single provider.

Start Program

Synergy Rx

Compounded semaglutide & tirzepatide — transparent pricing

From $199/mo

Drug

Compounded Sema / Tirze

Coaching

No

States

Most states

Best For

Mid-range compounded

Straightforward compounded GLP-1 at a transparent mid-range price. No coaching upsells.

Check Pricing

Embody GLP-1

Flexible Plans

Medically guided GLP-1 treatment — flexible plans

From $249/mo

Drug

Semaglutide

Coaching

Basic

States

Most states

Best For

Flexible plans

Multiple plan tiers so you can start lean and upgrade as needed.

View Plans

Care Bare Rx

GLP-1 medication with dedicated provider support

From $199/mo

Drug

Semaglutide

Coaching

Provider support

States

Most states

Best For

Provider-supported

Includes dedicated provider follow-ups — more hand-holding than a standard telehealth script.

View Plans

TrimRx

Doctor Consultations

Personalized GLP-1 with doctor consultations and tailored prescriptions

From $199/mo

Drug

Semaglutide / Tirzepatide

Coaching

Doctor consultations

States

50 states

Best For

Personalized care

Personalized doctor consultations with every plan — tailored prescriptions based on your health profile. Available in all 50 states.

Get Started

Strut Health

⚠️ FDA Notice

Compounded semaglutide and tirzepatide — fast, online, delivered

From $125/mo

Drug

Semaglutide / Tirzepatide

Coaching

Async provider support

States

Most states

Best For

Lowest price

One of the lowest-price compounded semaglutide programs available. ⚠️ FDA notice: Strut received a warning letter in February 2026 for marketing claims implying equivalence to branded drugs. The company updated its website to comply. Products are compounded and not FDA-approved.

See Program

Bodybuilding Health+

Bundle Discounts

Compounded GLP-1 in single dose or bundle plans — save up to 30% with multi-month bundles

From $96/mo

Drug

Compounded Semaglutide

Coaching

No

States

50 states

Best For

Bundle savings

Backed by the Bodybuilding.com brand with licensed pharmacy fulfillment. Single-dose to 12-month bundles save up to 30%. Microdosing protocol available for those easing in. Available in all 50 states.

See Plans

Eden Health

Multi-Category

GLP-1 + hormone, hair, NAD+ and longevity — 100k+ members, all in one platform

From $149/mo

Drug

GLP-1 + Hormone / NAD+ / Hair

Coaching

Licensed provider consultations

States

50 states

Best For

Multi-condition

One of the largest multi-vertical telehealth platforms with 100k+ members. Beyond weight loss — hormones, hair, NAD+, and longevity under one roof. Licensed provider consultations included. $100 discount baked into affiliate link.

Start Intake

Novi Weight Loss

Personalized GLP-1 with licensed provider consultation included — semaglutide and tirzepatide

Personalized — from ~$199/mo

Drug

GLP-1 (Semaglutide / Tirzepatide)

Coaching

Yes — licensed provider consultation included

States

50 states

Best For

Provider-led

Every patient starts with a comprehensive licensed provider consultation before any prescription is written. Personalized dosing plan tailored to your health profile from day one. Available in all 50 states.

Get Started

System Labs

NAD+ Available

GLP-1, NAD+, sermorelin, glutathione and longevity protocols — performance-first telehealth

From $59/mo

Drug

GLP-1, NAD+, Sermorelin, Glutathione

Coaching

Licensed U.S. clinician support

States

50 states

Best For

Longevity focus

Performance and longevity-focused platform offering peptides, GLP-1, NAD+, sermorelin, and glutathione alongside preventative protocols. Licensed U.S. clinician support. No insurance required, direct to door. Available in all 50 states.

View Programs

Wellorithm

✨ New

Board-certified obesity specialists + compounded GLP-1 — oral or injectable, money-back guarantee

From $147/mo

Drug

Semaglutide / Tirzepatide (compounded, oral or injectable)

Coaching

Yes — board-certified obesity medicine specialist

States

Most states (excl. LA)

Best For

Specialist oversight

One of the only programs staffed by board-certified obesity medicine specialists. Offers a refund guarantee if 10% body weight is not lost in 16 weeks. Rare oral (pill/sublingual) and injectable options. Not available in Louisiana.

View Wellorithm Plans

Tonik

Hormone + GLP-1

GLP-1 + hormone optimization — integrated weight loss and wellness protocols

From $199/mo

Drug

Semaglutide / Tirzepatide

Coaching

Licensed provider consultations

States

Most states

Best For

Hormone + GLP-1 combo

Combines GLP-1 weight loss with hormone optimization protocols — ideal for patients whose weight issues may have a hormonal component. Licensed provider consultations included.

View Program

EnhanceMD

Doctor-led GLP-1 + hormone, peptide and wellness protocols

From $212/mo

Drug

Semaglutide / Tirzepatide

Coaching

Provider consultations

States

Most states

Best For

Provider-led care

Doctor-led telehealth combining GLP-1 weight loss with hormone and peptide protocols. Personalized treatment plans with licensed provider consultations. Not available in some southern/midwest states.

Get Started

Frequently Asked Questions

What is the cheapest GLP-1 program available?
DudeMeds currently starts at $30/mo, making it one of the lowest-priced compounded semaglutide programs we've found. These are compounded semaglutide programs — not branded Ozempic or Wegovy.
Can I get a GLP-1 without insurance?
Yes. All of our affiliate partner programs are cash-pay telehealth providers — no insurance required. You'll see a licensed provider online, get a prescription if appropriate, and have medication shipped directly to you. Prices range from $30 to $300+/mo.
What's the difference between compounded and branded GLP-1?
Branded GLP-1s (Ozempic, Wegovy, Mounjaro, Zepbound) are FDA-approved and made by pharmaceutical companies. Compounded GLP-1s contain the same active ingredient (semaglutide or tirzepatide) but are mixed by a licensed compounding pharmacy — they are not FDA-approved branded drugs. Compounded versions are significantly cheaper.
Is semaglutide the same as Ozempic?
Semaglutide is the active ingredient in Ozempic (for diabetes) and Wegovy (for weight loss). Compounded semaglutide contains the same molecule but is not the branded product. It is not approved by the FDA as a finished drug product.
How long do I need to take a GLP-1 medication?
Clinical trials show weight tends to return when GLP-1 medications are stopped. Most providers recommend a minimum 12-month program for meaningful results. Some people continue indefinitely as a maintenance medication. Discuss your goals and timeline with your prescriber.
Are these telehealth GLP-1 programs legitimate?
Yes — the providers listed here are licensed telehealth platforms operating under state medical board regulations. Prescriptions are written by licensed physicians or nurse practitioners. Medications are dispensed by state-licensed compounding pharmacies. We verify each partner before listing.
What is the average monthly cost for a GLP-1 program?
Compounded semaglutide programs through telehealth typically run $100–$300/mo depending on the provider and dose. Branded Ozempic/Wegovy without insurance can exceed $1,000/mo at retail pharmacies. Our calculator above can help you estimate your total annual cost.
Which GLP-1 program has the best money-back guarantee?
SHED offers the strongest guarantee we've found: lose 10% of your body weight or receive a full refund. Wellorithm also offers a refund guarantee if 10% body weight is not lost in 16 weeks.
Does SkinnyRx really offer GLP-1 pills instead of injections?
Yes. SkinnyRx is one of the only telehealth providers offering compounded semaglutide and tirzepatide in oral tablet and sublingual formats — not just injections. This makes it a standout option for people who are needle-averse. Note that oral GLP-1 bioavailability differs from injectable formulations; discuss this with your provider during intake.
What else can I treat through Eden Health besides weight loss?
Eden Health is a multi-vertical telehealth platform that goes well beyond GLP-1 weight loss. Through the same platform, you can access treatment for hormone imbalances, hair loss, NAD+ therapy, and other longevity and wellness protocols. With 100k+ members and licensed provider consultations, it's one of the more comprehensive telehealth platforms available.
Is Bodybuilding Health+ a legitimate GLP-1 program?
Yes. Bodybuilding Health+ is affiliated with the Bodybuilding.com brand and uses licensed compounding pharmacies for medication fulfillment. The program offers compounded semaglutide starting at $199/mo with bundle options that can save up to 30%. They also offer a microdosing protocol for those easing into GLP-1 therapy. Available in all 50 states.

Affiliate disclosure: GLP1CostCalculator.com may earn a commission when you sign up with a provider through links on this page, at no additional cost to you. We only list programs we have independently reviewed. Compounded GLP-1 medications require a valid prescription from a licensed provider. Compounded medications are not FDA-approved finished drug products. Prices and availability vary by state and are subject to change. This page is for informational purposes only and does not constitute medical advice.