How to Use TrumpRx.gov to Save on Ozempic and GLP-1 Medications

The most expensive thing about TrumpRx.gov isn't using it. It's not knowing how. I spent six years in insurance billing watching patients walk away from perfectly good assistance programs because the process felt too complicated, too uncertain, or too easy to get wrong. TrumpRx is actually straightforward — but only if someone walks you through it. That's what this is.

By the end of this guide, you'll know exactly who qualifies, which GLP-1 drugs are covered, how to get your authorization, and where to fill your prescription at the MFN-negotiated price. Let's go step by step.

Step 1: Confirm You're Eligible

TrumpRx.gov is designed for Americans who are uninsured or underinsured — patients who have been paying full retail or near-retail prices for their GLP-1 medications without meaningful coverage assistance. Here's how eligibility typically breaks down:

• Uninsured: No health insurance at all. You are almost certainly eligible. TrumpRx was built for exactly this situation.
• Underinsured with commercial coverage that excludes GLP-1s: Many employer health plans cover GLP-1s for diabetes but explicitly exclude them for weight management. If your insurance refuses to cover your GLP-1 prescription, TrumpRx eligibility likely applies to you.
• High-deductible plan, still in deductible phase: If you're paying full cost before your deductible kicks in, TrumpRx may offer better pricing than your in-network pharmacy rate. Check the portal — eligibility for this group varies.
• Medicare beneficiaries: Medicare has a separate drug pricing track under the Inflation Reduction Act. TrumpRx generally does not stack with Medicare coverage. If you're on Medicare, your best path is typically Medicare Part D negotiated pricing or the Extra Help program.
• Medicaid beneficiaries: Medicaid has its own drug pricing framework. TrumpRx is not intended to layer on top of Medicaid benefits.

When in doubt: go to TrumpRx.gov and complete the eligibility questionnaire. It takes under five minutes and gives you a definitive answer. Don't assume — check.

Step 2: Search for Your GLP-1 Medication

Once you're on TrumpRx.gov, search for your medication by its brand name:

• Ozempic — semaglutide injection, Novo Nordisk (for type 2 diabetes)
• Wegovy — semaglutide injection, Novo Nordisk (for weight management)
• Mounjaro — tirzepatide injection, Eli Lilly (for type 2 diabetes)
• Zepbound — tirzepatide injection, Eli Lilly (for weight management)

The portal will display the current MFN-negotiated price for your medication and dose. As of May 2026, confirmed prices include Ozempic at approximately $285/month and Wegovy at approximately $349/month. Tirzepatide pricing through TrumpRx continues to be finalized — check the portal directly for the most current numbers.

Here's what they don't tell you: always search for both the brand name and the generic name (semaglutide, tirzepatide). The portal may list the same medication under slightly different naming conventions depending on dose and formulation.

Step 3: Complete the Authorization

After confirming your medication is available at an MFN price and verifying your eligibility, the portal walks you through a brief authorization process. You'll need:

• A valid prescription from your prescribing physician (your current Rx is fine — you don't need a new one)
• Basic personal information for the eligibility determination
• Your pharmacy preference (zip code search available for participating locations)

The portal generates an authorization code or voucher that you bring to the participating pharmacy. Think of it like a GoodRx coupon, but backed by federal purchasing authority rather than a PBM negotiated rate. The mechanism is different; the patient experience at the pharmacy counter is similar.

Step 4: Find a Participating Pharmacy

Not every pharmacy participates in TrumpRx. The portal's pharmacy locator, searchable by zip code, shows you which pharmacies near you are accepting TrumpRx authorizations. As of the May 2026 expansion, major chains — including CVS, Walgreens, Rite Aid, and Walmart Pharmacy — are participating in most markets. Many independent pharmacies are as well.

If your usual pharmacy isn't listed, call them before assuming they don't participate — the network is expanding rapidly, and some pharmacies are enrolled but not yet fully reflected in the portal's locator. Your pharmacist can confirm in under a minute whether they're accepting TrumpRx vouchers.

Step 5: Fill Your Prescription at the MFN Price

At the pharmacy, present your prescription, your TrumpRx authorization, and your ID. The pharmacist processes the transaction at the MFN-negotiated rate. You pay the MFN price — approximately $285 for Ozempic or $349 for Wegovy, depending on your medication — rather than the retail rate.

Save your receipt. If the pharmacy charges you full retail despite your TrumpRx authorization, ask them to reprocess. If you encounter a persistent issue, TrumpRx.gov has a dispute resolution contact — use it. The price discrepancy you might be disputing is hundreds of dollars, and it's worth a phone call.

How to Compare TrumpRx Against Your Other Options

Before committing to TrumpRx as your primary savings strategy, I'd encourage every patient to run a full comparison. TrumpRx is often the best option for uninsured GLP-1 patients — but not always, and not for everyone. Use our GLP-1 cost calculator to compare TrumpRx pricing against:

• Your current out-of-pocket cost (baseline)
• Manufacturer savings cards (best for commercially insured patients)
• GoodRx pricing at your nearest pharmacies
• Telehealth compounded GLP-1 program pricing

The calculator gives you a side-by-side that accounts for your specific drug, dose, and insurance situation. It takes about 60 seconds.

What to Do If You Don't Qualify for TrumpRx

Not everyone will qualify, and I want to be direct about that rather than leaving you with a dead end. If TrumpRx doesn't apply to your situation — because you have Medicare, because your income or insurance status doesn't meet the eligibility criteria, or because your medication isn't yet in the covered portfolio — here are the next-best options:

1. Manufacturer patient assistance programs: Novo Nordisk's NovoCare program and Eli Lilly's assistance programs can bring costs to $0 for qualifying uninsured or low-income patients. Check both programs directly — eligibility is broader than many patients expect.
2. Manufacturer copay savings cards: For commercially insured patients, these can reduce monthly cost to $0-$25 regardless of what you'd otherwise pay.
3. Telehealth compounded GLP-1 programs: Starting at $125-$200/month for compounded semaglutide with licensed provider access included — a different product than brand-name GLP-1s, but often effective and price-accessible.

Quick Reference: TrumpRx at a Glance

• Portal: TrumpRx.gov
• Launched: February 5, 2026; major expansion May 18, 2026
• Coverage: 17 manufacturers, 86% of branded drug market
• GLP-1s covered: Ozempic, Wegovy, Mounjaro, Zepbound
• Ozempic MFN price: ~$285/month (vs ~$900 retail)
• Wegovy MFN price: ~$349/month (vs ~$1,350 retail)
• Best for: Uninsured and underinsured patients paying out-of-pocket
• Not applicable for: Medicare and Medicaid beneficiaries with existing drug coverage

The process is not complicated. The eligibility check is fast. The price difference is $615 a month for Ozempic — the kind of number that changes whether treatment is feasible for most households. Start at TrumpRx.gov, run your numbers in our calculator, and fill your prescription at the price it should have been all along.