The price you pay for a GLP-1 medication in 2026 depends on three factors: which drug your doctor prescribes, whether you have insurance, and — if you are on Medicaid — which state you live in. Without insurance, a monthly supply of Ozempic costs approximately $935. With Medicaid in a coverage-friendly state, your cost may be close to zero. This guide breaks down what real patients pay, state by state, with current data from CMS.gov and manufacturer pricing.
GLP-1 Drug Retail Prices (2026, Without Insurance)
GLP-1 medication insurance coverage by state 2026 · Source: IQVIA · CMS · glp1costcalculator.com
| Drug | Manufacturer | Primary Use | Monthly Cost |
|---|---|---|---|
| Ozempic (semaglutide inject.) | Novo Nordisk | Type 2 diabetes | $935–$970 |
| Wegovy (semaglutide inject.) | Novo Nordisk | Chronic weight management | $1,349 |
| Mounjaro (tirzepatide inject.) | Eli Lilly | Type 2 diabetes | $1,069 |
| Zepbound (tirzepatide inject.) | Eli Lilly | Chronic weight management | $1,059 |
| Rybelsus (oral semaglutide) | Novo Nordisk | Type 2 diabetes | $935 |
| Compounded semaglutide | 503B compounders | Off-label weight loss | $150–$450 |
Medicaid Coverage for Weight-Loss GLP-1s by State (2026)
Coverage for GLP-1 medications prescribed specifically for obesity varies dramatically. Diabetes indications are more broadly covered; obesity indications are where costs diverge most sharply.
| State | Covers Obesity GLP-1s | Key Restrictions | Est. Monthly OOP |
|---|---|---|---|
| Illinois | Yes | Prior auth; BMI 30+ | $0–$5 |
| Oregon | Yes | Preferred drug list criteria | $0–$3 |
| Washington | Yes | PA required; step therapy may apply | $0–$5 |
| Minnesota | Yes | PA required; BMI criteria | $0–$5 |
| New York | Partial | Covered with extensive PA requirements | $0–$50 |
| California | Partial | Medi-Cal: BMI 35+ or comorbidities required | $0–$60 |
| Texas | No | Not on preferred drug list for obesity | $935–$1,349 |
| Florida | No | Not covered for weight management | $935–$1,349 |
| Georgia | No | Not covered for obesity indication | $935–$1,349 |
How to Reduce Your Cost Regardless of State
- Manufacturer savings cards: NovoCare can reduce Ozempic/Wegovy to as low as $25/month for commercially insured patients. Eli Lilly's savings card can bring Mounjaro/Zepbound to $25/month.
- Cost Plus Drugs: Mark Cuban's platform offers semaglutide tablets near cost, typically 80-90 percent below retail.
- 503B compounders: Compounded semaglutide available at $150-$450/month, though FDA oversight is tightening as shortage status resolves.
- GoodRx and discount programs: Can reduce retail cost by 15-40 percent at participating pharmacies.
Methodology
Retail pricing sourced from manufacturer published list prices and pharmacy benefit manager (PBM) data as of April 2026. Medicaid coverage data compiled from individual state Medicaid agency preferred drug lists and CMS.gov coverage summaries. Out-of-pocket estimates assume standard Medicaid cost-sharing of $1-$5 for covered drugs.
Calculate Your GLP-1 Out-of-Pocket Cost
Your exact monthly cost depends on your specific insurance plan, state Medicaid rules, and prescribed medication. Use our GLP-1 cost calculator to estimate what you will pay based on your insurance status, state, and drug.